นิตยสาร สสวท. ฉบับที่ 235

ป‚ที่ 50 ฉบับที่ 235 มีนาคม - เมษายน 2565 37 Bendjeddou, D & Lalaoui, K & Satta, D. (2003). Immunostimulating activity of the hot water-soluble polysaccharide extracts of Anacyclus pyrethrum, Alpinia galanga and Citrullus colocynthis. Journal of ethnopharmacology. 88 (2-3): 155-60. Chiow, K & Phoon, M & Putti, T & Tan, BK & Chow, VT.(2016). Evaluation of antiviral activities of Houttuynia cordata Thunb. extract, quercetin, quercetrin and cinanserin on murine coronavirus and dengue virus infection. Asian Paci¾c journal of tropical medicine. 9 (1): 1-7. COVID-19 Dashboard by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University (JHU)”. ArcGIS. Johns Hopkins University. Retrieved July 18, 2021, from https://gisanddata.maps.arcgis.com/apps/dashboards/bda7594740fd40299423467b48e9ecf6. Gupta, S & Mishra, K & Ganju, L. (2017). Broad-spectrum antiviral properties of andrographolide. Archives of virology. 162 (3): 611-23. Mwidau, J & Chang, D. (2010). Clinical Trials: Why Participate? Early Diagnosis and Treatment of Cancer Series. Colorectal Cancer E-Book: Expert Consult. Rathinavel, T & Palanisamy, M & Palanisamy, S & Subramanian, A & Thangaswamy S. (2020). Phytochemical 6-Gingerol–A promising Drug of choice for COVID-19. I nt J Adv Sci Eng. (4): 1482-9. Rousseaux, CG & Bracken, WM.(2013). Overview of Drug Development. Haschek and Rousseaux’s Handbook of Toxicologic Pathology: Elsevier. Sa-Ngiamsuntorn K & Suksatu, A & Pewkliang, Y & Thongsri, P & Kanjanasirirat, P & Manopwisedjaroen, S et al. (2021). Anti-SARS-CoV-2 activity of Andrographis paniculata extract and its major component Andrographolide in human lung epithelial cells and cytotoxicity evaluation in major organ cell representatives. Journal of Natural products. 84 (4): 1261-70. Suebsasana, S & Pongnaratorn, P & Sattayasai, J & Arkaravichien, T & Tiamkao, S & Aromdee, C. (2009). Analgesic, antipyretic, anti-in¿ammatory and toxic effects of andrographolide derivatives in experimental animals. Archives of pharmacal research. 32 (9): 1191-200. Xu, Y. (2009). Adaptive Immune Response-modifying and Antimicrobial Properties of Andrographis paniculata and Andrographolide [Dissertation Doktor]. The Department of Biological and Physical Science The University of Queensland. Yan, J & Shen, X & Cao, Y & Zhang, J & Wang, Y & Cheng, Y. (2020). Discovery of Anti-2019-nCoV Agents from 38 Chinese Patent Drugs toward Respiratory Diseases via Docking Screening. Preprints, Article ID: 2020020254. ¡ÃÁ¡ÒÃᾷἹä·ÂáÅСÒÃᾷ·Ò§àÅ×Í¡ ¡ÃзÃǧÊÒ¸ÒóÊØ¢. (2564). ¤íÒá¹Ð¹íÒ¡ÒÃ㪌ÂÒ¿‡Ò·ÐÅÒÂâ¨ÃÊíÒËÃѺ¡ÒõԴàª× éÍäÇÃÑÊâ¤âÃ¹Ò 2019 (COVID-19). ¡Ãا෾ÁËÒ¹¤Ã: ºÃÔÉÑ· ÊÒÁà¨ÃԾҳԪ (¡Ãا෾) ¨íÒ¡Ñ´. à͹¡ ÁØ ‹§ÍŒÍÁ¡ÅÒ§. àÍ¡ÊÒûÃСͺ¡ÒÃàÊǹÒÇÔªÒ¡Òà ¿‡Ò·ÐÅÒÂâ¨Ã ÊÁعä¾Ãä·Âã¹Çԡĵ COVID-19 ¡ÃÁ¡ÒþѲ¹Ò¡ÒÃᾷἹä·ÂáÅСÒÃᾷ·Ò§àÅ×Í¡ ¡ÃзÃǧÊÒ¸ÒóÊØ¢. [facebook post]. Ê׺¤Œ¹àÁ× èÍ 16 ÁԶعÒ¹ ¾.È. 2564. ¨Ò¡ https://www.facebook.com/biothai.net/posts/4353405928031228. ¤íÒá¹Ð¹íÒ¡ÒÃ㪌¿‡Ò·ÐÅÒÂâ¨ÃÊíÒËÃѺâäâ¤ÇÔ´ - 19 (¡ÃÁ¡ÒÃᾷἹä·ÂáÅСÒÃᾷ·Ò§àÅ×Í¡ ¡ÃзÃǧÊÒ¸ÒóÊØ¢, 2019) • ÊíÒËÃѺ¼ÙŒ»†Ç·ÕèäÁ‹ÁÕÍÒ¡Òà (Asymptomatic COVID - 19) á¹Ð¹íÒãˌ㪌ÂÒ¿‡Ò·ÐÅÒÂâ¨Ã·ÕèÁÕ»ÃÔÁÒ³ Andrographolide 20 ÁÔÅÅÔ¡ÃÑÁ ÇѹÅÐ 3 ¤ÃÑ é§ ¡‹Í¹ÍÒËÒÃ àªŒÒ ¡ÅÒ§Çѹ áÅÐàÂç¹ µÔ´µ‹Í¡Ñ¹¹Ò¹ 5 Çѹ • ÊíÒËÃѺ¼Ù Œ»†ÇÂ·Õ èÁÕÍÒ¡ÒÃäÁ‹Ãعáç äÁ‹ÁÕ»˜¨¨ÑÂàÊÕ è§µ‹Í¡ÒÃ໚¹âä ÃعáçáÅÐâä»Í´ÍÑ¡àʺ (Symptomatic COVID-19 without Pneumonia and No Risk Factors for Severe Disease) á¹Ð¹íÒãˌ㪌ÂÒ¿‡Ò·ÐÅÒÂâ¨Ã·Õ èÁÕ»ÃÔÁÒ³ Andrographolide 60 ÁÔÅÅÔ¡ÃÑÁ ÇѹÅÐ 3 ¤ÃÑ é§ ¡‹Í¹ÍÒËÒÃ àªŒÒ ¡ÅÒ§Çѹ áÅÐàÂç¹ µÔ´µ‹Í¡Ñ¹¹Ò¹ 5 Çѹ • ÊíÒËÃѺ¼ÙŒ·Õ赌ͧ¡ÒÃàÊÃÔÁÀÙÁԤ،Á¡Ñ¹ á¹Ð¹íÒãˌ㪌ÂÒ¿‡Ò·ÐÅÒÂâ¨Ã·Õ èÁÕ»ÃÔÁÒ³ Andrographolide 10 ÁÔÅÅÔ¡ÃÑÁ ÇѹÅÐ 1 ¤ÃÑ é§ µÔ´µ‹Í¡Ñ¹¹Ò¹ 5 Çѹ ànj¹ 2 Çѹ µÔ´µ‹Í¡Ñ¹äÁ‹à¡Ô¹ 12 ÊÑ»´Òˏ ·Ñ駹Õé ¼ÙŒ»†Ç·ÕèµÔ´àª×éͤÇÃ䴌ÃѺ¡Òà ´ÙáŵÒÁËÅÑ¡ÁҵðҹáÅÐÃѺ¡Òè‹ÒÂÂÒ â´ÂÍÂً㹡ÒäǺ¤ØÁ¢Í§á¾·ÂÍ‹ҧã¡ÅŒªÔ´ ( ¡ÃÁ¡ÒÃᾷ á¼¹ä·ÂáÅСÒÃᾷ ·Ò§àÅ×Í¡ ¡ÃзÃǧÊÒ¸ÒóÊØ¢, 2019) ¢ŒÍ¤ÇÃÃÐÇѧ (¡ÃÁ¡ÒÃᾷἹä·ÂáÅСÒÃᾷ·Ò§àÅ×Í¡ ¡ÃзÃǧÊÒ¸ÒóÊØ¢, 2019) • ¿‡Ò·ÐÅÒÂâ¨ÃÁÕÄ·¸Ô ìàÂç¹ Ëҡ㪌µÔ´µ‹Í¡Ñ¹à¡Ô¹ÃÐÂÐàÇÅÒ·Õ èá¹Ð¹íÒ ÍÒ¨·íÒãˌᢹ¢ÒªÒ ͋͹áç ÃٌÊ֡˹ÒÇàÂç¹ÀÒÂã¹ • ¡ÒÃ㪌¿‡Ò·ÐÅÒÂâ¨ÃËÇÁ¡ÑºÂÒÅ´¤ÇÒÁ´Ñ¹âÅËÔµ (Antihyper- tensives) ÍÒ¨àÊÃÔÁÄ·¸Ôì¡Ñ¹ • äÁ‹¤ÇÃ㪌¿‡Ò·ÐÅÒÂâ¨ÃËÇÁ¡ÑºÂÒµŒÒ¹¡ÒÃá¢ç§µÑǢͧàÅ×Í´ (Anticoagulants) ÂÒµŒÒ¹à¡Åç´àÅ×Í´ (Antiplatelets) ÂÒµŒÒ¹«ÖÁàÈÃŒÒ (Antidepressant) ઋ¹ Clozapine, Fluvoxamine, Olanzapine ÂÒºÃÃà·Ò ÍÒ¡ÒÃÍÑ¡àʺ·Õ èäÁ‹ãª‹ÊàµÕÂÃÍ´ (NSAIDs) ËÃ×ÍÂÒᡌ»Ç´¢ŒÍµ‹Ò§æ ઋ¹ Diclofenac, Ibuprofen • ºÒ§ÃÒÂÍÒ¨à¡Ô´ÍÒ¡ÒÃäÁ‹¾Ö§»ÃÐʧ¤ ઋ¹ »Ç´·ŒÍ§ ·ŒÍ§àÊÕ ¤Å×è¹äʌ ã¨ÊÑè¹ ¼Ô´»¡µÔà¡ÕèÂǡѺ¼ÔÇ˹ѧ • ˌÒÁ㪌ã¹ËÔ§·Õ èµÑ 駤ÃÃÀ ËÃ×ÍÍÒ¨¨ÐµÑ 駤ÃÃÀ áÅÐ·Õ è¡íÒÅѧ ãˌ¹ÁºØµÃ à¾ÃÒÐÍÒ¨·íÒãˌ·Òá¼Ô´ÃÙ» ¨ÐàËç¹ä´ŒÇ‹Ò ¿‡Ò·ÐÅÒÂâ¨ÃÁÕá¹Ç⹌Á·Õ è¨Ð¹íÒÁÒ㪌㹡ÒÃÃÑ¡ÉÒâä Covid-19 ã¹¼Ù Œ»†ÇÂ·Õ èÍÒ¡ÒÃäÁ‹Ãعáç䴌 ËÃ×ÍÍÒ¨ãªŒã¹¡Ã³Õ·Õ èµŒÍ§¡ÒÃàÊÃÔÁ ÀÙÁÔ¤Ø ŒÁ¡Ñ¹ ᵋÍ‹ҧäáçµÒÁ ¼ÙŒ»†Ç¡ç¨íÒ໚¹µŒÍ§ÍÂÙ ‹ã¹¤ÇÒÁ´ÙáŢͧᾷ áÅÐ㪌ÂÒµÒÁ¢ŒÍº‹§ªÕ éã¹»ÃÔÁÒ³·Õ èàËÁÒÐÊÁ áÁŒÇ‹Ò»˜¨¨ØºÑ¹¨ÐÁÕ·Ñ é§ÊÁعä¾Ã ÂÒÃÑ¡ÉÒâä áÅÐÇѤ«Õ¹»‡Í§¡Ñ¹âä Covid - 19 ᵋ·Ø¡¤¹¡çÂѧ¤§µŒÍ§´ÙáÅ ÊØ¢ÀҾËҧ¡Ò¢ͧµ¹àͧãˌá¢ç§áç ÍÍ¡¡íÒÅѧ¡ÒÂÍ‹ҧÊÁè íÒàÊÁÍ áÅРŌҧÁ×ÍãˌÊÐÍÒ´ ÊÇÁãʋ˹ŒÒ¡Ò¡Í¹ÒÁÑÂàÁ× èÍÍÂÙ ‹ã¹¾× é¹·Õ èàÊÕ è§·Ø¡¤ÃÑ é§ áÅÐ ¤ÍµԴµÒÁ¢ŒÍÁÙÅ¢‹ÒÇÊÒÃÍ‹ҧÊÁèíÒàÊÁÍ บรรณานุกรม